Following the recent release of the 2021 NFL regular season schedule, many fans are thrilled with some of the matchups that we will see.
There will be multiple games that could have major playoff implications, as well as a few potential super bowl LVI showdowns.
With many postseason contenders in both the AFC and NFC, this year is poised to be one of the most exciting ones in recent memory.
In addition to the many talented roster’s across the league, the NFL expanded it’s schedule to 17 games, making this season the largest one ever.
Here’s a look at the five can’t miss matchups for next season.
5. Kansas City Chiefs @ Green Bay Packers: Week 12 – 4:25pm EST
Primetime football in Lambeau Field is always an exciting event.
In week 8, Patrick Mahomes and the Kansas City Chiefs will head to Green Bay in hopes of getting revenge from their 2019 loss at home to the Packers.
While Aaron Rodgers was able to steal a victory in Arrowhead Stadium a few years ago, the second time around may not be as easy.
In their previous matchup, Patrick Mahomes was injured, leaving the job to backup quarterback Matt Moore. As a result of this, the Chiefs came up short, losing 24-31.
As the two super bowl contenders meet again, they are both looking to have bounce back seasons.
The Packers hope to get over their NFC championship struggles, and the Chiefs will look to re-claim the super bowl title that they had just two years ago.
4. Buffalo Bills @ Kansas City Chiefs: Week 5 – 8:20pm EST
In this week 5 matchup, Josh Allen and the Bills head to Arrowhead Stadium to take on Patrick Mahomes and the Chiefs on Sunday night football.
This will be their first meeting since last year’s AFC championship game, where Kansas City won 38-24.
Buffalo has established themselves as one of the best teams in all of football, winning their division for the first time since 1995, and coming within one game of the super bowl last season.
Kansas City on the other hand, is looking to win their third straight conference title. With the addition of three potential starting offensive lineman, their hopes at remaining the team to beat come postseason time still stand.
This game could have both playoff implications, and gives us a preview of a potential round three meeting in the AFC championship game.
3. Buffalo Bills @ Tampa Bay Buccaneers: Week 14 – 4:25pm EST
Another potential super bowl preview in week 14 in Tampa Bay.
The Bucs will host the Bills in what is poised to be one of the best games of the season.
While nobody has more wins against a team in their career as Tom Brady does verses Buffalo, the Bills are not the same team as they once were.
Led by Josh Allen, the team from upstate New York has pro bowl talent throughout their roster.
Once dominated by Brady in New England, the Bills are looking to get their revenge in Raymond James Stadium, where Tampa Bay won the super bowl last year.
Both of these teams will once again be championship contenders, and hope to meet for round two in February at SoFi Stadium.
2. Kansas City Chiefs @ Baltimore Ravens: Week 2 – 8:20pm EST
This early season matchup in Baltimore could be another playoff preview.
In week 2, the Ravens will host the Chiefs in what will be another important Sunday night football showdown.
The two former MVP’s, Patrick Mahomes and Lamar Jackson, have had a few head-to-head matchups already. However, the Kansas City seems Baltimore’s number.
Mahomes is 3-0 against Jackson in his career so far, helping his team score 27 points or more in each of those meetings.
Baltimore is another AFC team who seems to have all the pieces made for a super bowl.
But, much like Buffalo, the Ravens have one obstacle standing in their way; Mahomes and the Chiefs.
1. Tampa Bay Buccaneers @ New England Patriots: Week 4 – 8:20pm EST
This season has many intriguing matchups scattered across the schedule.
However, no game will be more anticipated than the return of Tom Brady to New England in week 4 on Sunday night.
For the first time since his departure, Brady will head to Foxboro to face his former team and head coach, Bill Belichick.
The Patriots are coming off a disappointing first year without their hall of fame quarterback, finishing just 6-10 in 2020.
On the other hand, Tampa Bay is fresh off of a super bowl win, with all 22 of their starters returning.
While this game may not be a super bowl matchup, all eyes will be on it as Brady returns to the place where he won his first six titles.
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